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INTERACTIVE STRUCTURAL MASS SPECTROMETRY

HDX-MS Explorer

Trace the reported ALC1 HDX1 (319–357), HDX2 (392–415) and HDX3 (832–858) regions after tri-ADP-ribose binding, then import source peptide data for quantitative filtering and time-course inspection.

DATA STATUSPublished evidence mapSingh et al. · Molecular Cell · 2017
Sequence coverage82.2%reported for full-length ALC1
Changed peptides10 + 1 lateFigure S4 peptide ranges
Significance rule0.52 D98.75% confidence · n = 3

Published peptide-region map

Reported HDX increase60 min only

Published HDX-MS time points

The paper sampled 0.25, 1, 10 and 60 minutes. Exact peptide-level uptake magnitudes are not reconstructed from the plotted figure.

Published peptide evidence

RegionPeptideRangeObservationTiming