Science · Data · AI · Products

Hari Raj Singh Dr. rer. nat.

Molecular Cell Biologist · Scientific Programme Builder · AI-enabled Biology

From molecular mechanisms to connected biological systems, predictive models and evidence-aware scientific programmes.

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15+ yrsInternational scientific experience

16 worksLinked research and outputs

Cross-scaleMolecules · cells · data

Open a direction

One profile. Four working surfaces.

01 · SCIENCE

Mechanism → organisation → phenotype

Cell biology, chromatin, mesoscale organisation and research programmes.

Open Research → 02 · DATA × AI

Prediction made inspectable

Interactive labs, modelling, data systems and AI-enabled biology.

Open Bio × AI → 03 · PORTFOLIO

Map · Connect · Build

Mechanism, measurement and modelling expressed as a visual scientific portfolio.

Open Portfolio → 04 · EVIDENCE

Research record, linked

Peer-reviewed papers, tools, data platforms, preprints and scientific commentary.

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HRS App is a mobile launch surface for the public profile at hari-raj-singh.com.

Selected work

Mechanism, organisation and prediction.

01

ALC1 activation and chromatin regulation

PAR-triggered release of auto-inhibition connecting protein state to chromatin remodelling.

02

TRIMCode · mesoscale cellular organisation

Sequence, modular architecture, variants, localisation and disease-associated cellular states.

03

PICNIC predictive biology

Sequence and structure features translated into condensate-forming protein prediction and validation.

04

Bio × AI learning and product interfaces

Interactive scientific interfaces for supervised ML, visualisation, language AI and living-function reasoning.

Capabilities

Across biological scales.

Connected practice

Experimental depth with quantitative reach.

Molecular cloning and engineering, quantitative cell biology and imaging, protein structure–function reasoning, data analysis, machine learning, scientific platforms and evidence-aware programme development.

Cell biologyChromatinBioimagingHuman geneticsPredictive biologyPythonScientific products

Evidence

Selected evidence.

Single first author2017

A poly(ADP-ribose) trigger releases ALC1 autoinhibition

Molecular Cell · mechanistic discovery connecting ADP-ribose signalling, protein allostery and chromatin remodelling.

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Co-first author2024

PICNIC Accurately Predicts Condensate-Forming Proteins

Nature Communications · predictive biology with proteome-scale application and cellular validation.

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Co-first author2025

Mesoscale Landscaping of the TRIM Protein Family

bioRxiv · atlas-scale imaging and human genetics connecting TRIM variants to cellular organisation.

Open preprint ↗

Collaborative co-author2013

Structures of Drosophila Cryptochrome and Mouse Cryptochrome1

Cell · structural and mechanistic work connecting protein architecture, interactions and circadian function.

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View all 16 outputs → Visual portfolio

Profile

Scientific practice across scales.

Hari Raj Singh is an interdisciplinary molecular and cellular biologist working across mechanistic discovery, quantitative imaging, mesoscale cellular organisation, human genetics, AI-enabled prediction and scientific platform development.

Mechanistic biologyMesoscale organisationAI-enabled biologyResearch systems

Connect

Research, collaboration and opportunities.

EmailHari.R.Singh7@gmail.com↗ LinkedInProfessional profile↗ Google ScholarPublications and citations↗ ORCID0009-0006-7066-1754↗ Full websitehari-raj-singh.com→